Accel-KKR has launched RS2 Healthcare Partners, a dedicated healthcare technology investment vehicle, and closed its first transaction with a recapitalization of Loftware, an enterprise labeling and artwork management software company.

The deal provides RS2 with an initial platform asset that already counts many healthcare organizations among its customers.

Loftware’s platform automates the design, approval, and distribution of labels and packaging inserts for multinational companies operating across complex global supply chains.

The software is widely adopted in highly regulated industries—pharmaceuticals, medical devices, and life sciences—where compliance mandates exacting labeling accuracy and consistent brand presentation.

The company also serves consumer goods and other sectors with rigorous packaging requirements.

Accel-KKR, a technology-focused private equity firm with more than $19 billion in capital commitments, formed RS2 to pursue healthcare-IT opportunities.

Loftware’s existing management team will continue to lead the business under the new structure, and the capital infusion is intended to support product development and geographic expansion.

The recapitalization gives RS2 a platform with strong regulatory tailwinds, and the firm may consider add-on acquisitions that extend Loftware’s capabilities in compliance-intensive verticals.